| # | Institute Name | Location | Present Name / Updated Status & Key Notes |
| 1 | Indian Agricultural Research Institute (IARI) | New Delhi | Popularly known as Pusa Institute. |
| 2 | Central Rice Research Institute | Cuttack, Odisha | Renamed as ICAR – National Rice Research Institute (NRRI). |
| 3 | Central Sugarcane Research Institute | Coimbatore, Tamil Nadu | Officially known as ICAR – Sugarcane Breeding Institute (SBI). |
| 4 | Central Potato Research Institute (CPRI) | Shimla, Himachal Pradesh | ICAR – CPRI. |
| 5 | Central Tobacco Research Institute (CTRI) | Rajahmundry, Andhra Pradesh | ICAR – CTRI. |
| 6 | Central Forest Research Institute | Dehradun, Uttarakhand | Officially known as Forest Research Institute (FRI). |
| 7 | National Sugar Institute (NSI) | Kanpur, Uttar Pradesh | Under the Ministry of Consumer Affairs, Food and Public Distribution. |
| 8 | Indian Lac Research Institute | Ranchi, Jharkhand | Renamed as ICAR – National Institute of Secondary Agriculture (NISA) (formerly IINRG). |
| 9 | National Dairy Research Institute (NDRI) | Karnal, Haryana | ICAR – NDRI. |
| 10 | Central Fuel Research Institute (CFRI) | Dhanbad, Jharkhand | Merged: Combined with CMRI to form CSIR – Central Institute of Mining and Fuel Research (CIMFR). |
| 11 | Central Leather Research Institute (CLRI) | Chennai, Tamil Nadu | CSIR – CLRI. |
| 12 | Central Mining Research Institute (CMRI) | Dhanbad, Jharkhand | Merged: Combined with CFRI to form CSIR – Central Institute of Mining and Fuel Research (CIMFR). |
| 13 | Central Drug Research Institute (CDRI) | Lucknow, Uttar Pradesh | CSIR – CDRI. |
| 14 | India Meteorological Department (IMD) / Observatory | New Delhi & Pune | Primary weather and meteorological observatory in India. |
| 15 | Raman Research Institute (RRI) | Bengaluru, Karnataka | Autonomous research institute founded by Nobel laureate C.V. Raman. |
| 16 | Central Scientific Instruments Organisation (CSIO) | Chandigarh | CSIR – CSIO. |
| 17 | National Metallurgical Laboratory (NML) | Jamshedpur, Jharkhand | CSIR – NML. |
| 18 | Central Salt & Marine Chemicals Research Institute (CSMCRI) | Bhavnagar, Gujarat | CSIR – CSMCRI. |
| 19 | Archaeological Survey of India (ASI) & Indian Museum | Kolkata, West Bengal | ASI Headquarters is in New Delhi; Indian Museum is located in Kolkata. |
| 20 | Central Jute Technological Research Institute | Kolkata, West Bengal | Renamed as ICAR – National Institute of Natural Fibre Engineering and Technology (NINFET). |
| 21 | Central Coconut Research Institute | Kasaragod, Kerala | Renamed as ICAR – Central Plantation Crops Research Institute (CPCRI). |
| 22 | Textile Research Institute | Ahmedabad, Gujarat | Known as Ahmedabad Textile Industry’s Research Association (ATIRA). |
| 23 | All India Institute of Medical Sciences (AIIMS) | New Delhi | Premier medical research institute; now expanded across multiple cities. |
| 24 | National Aeronautical Laboratory | Bengaluru, Karnataka | Renamed as CSIR – National Aerospace Laboratories (NAL). |
| 25 | National Institute of Oceanography (NIO) | Dona Paula, Goa | CSIR – NIO. |
| 26 | National Geophysical Research Institute (NGRI) | Hyderabad, Telangana | CSIR – NGRI. |
| 27 | Indian Institute of Petroleum (IIP) | Dehradun, Uttarakhand | CSIR – IIP. |
| 28 | Central Building Research Institute (CBRI) | Roorkee, Uttarakhand | CSIR – CBRI. |
| 29 | Central Road Research Institute (CRRI) | New Delhi | CSIR – CRRI. |
| 30 | Tata Institute of Fundamental Research (TIFR) | Mumbai, Maharashtra | Premier basic research institution for physics, chemistry, and biology. |
| 31 | High Altitude Research Laboratory | Gulmarg, Jammu & Kashmir | Specialized laboratory under BARC / Department of Atomic Energy. |
| 32 | National Botanical Research Institute (NBRI) | Lucknow, Uttar Pradesh | CSIR – NBRI. |
| 33 | Central Food Technological Research Institute (CFTRI) | Mysore, Karnataka | CSIR – CFTRI. |
| 34 | Central Glass and Ceramic Research Institute (CGCRI) | Kolkata, West Bengal | CSIR – CGCRI. |
| 35 | National Environmental Engineering Research Institute (NEERI) | Nagpur, Maharashtra | CSIR – NEERI. |
| 36 | Central Electro-Chemical Research Institute (CECRI) | Karaikudi, Tamil Nadu | CSIR – CECRI. |
| 37 | Indian Institute of Chemical Biology (IICB) | Kolkata, West Bengal | CSIR – IICB. |
| 38 | Industrial Toxicology Research Centre (ITRC) | Lucknow, Uttar Pradesh | Renamed as CSIR – Indian Institute of Toxicology Research (IITR). |
| 39 | Central Mechanical Engineering Research Institute (CMERI) | Durgapur, West Bengal | CSIR – CMERI. |
| 40 | Centre for Cellular and Molecular Biology (CCMB) | Hyderabad, Telangana | CSIR – CCMB. |
| 41 | ISRO Satellite Centre (URSC) (Added) | Bengaluru, Karnataka | Primary centre for design and development of satellites. |
| 42 | Bhabha Atomic Research Centre (BARC) (Added) | Mumbai, Maharashtra | India’s primary nuclear research facility. |
| 43 | Defence Research and Development Organisation (DRDO) (Added) | New Delhi | Headquarters for military research & development. |
| 44 | Indian Institute of Science (IISc) (Added) | Bengaluru, Karnataka | Premier institution for advanced scientific & engineering research. |
| 45 | National Physical Laboratory (NPL) (Added) | New Delhi | CSIR – NPL; custodian of Indian standard measurements. |
| 46 | National Chemical Laboratory (NCL) (Added) | Pune, Maharashtra | CSIR – NCL; premier research centre for chemical sciences. |
